A. Champa Jayasuriya, Ph.D.
Professor of Orthopaedic Surgery and Bioengineering
Director of Orthopaedic Research
Department of Orthopaedic Surgery
ÃÛÌÒ´«Ã½ of Medicine and Life Sciences
The University of Toledo Health Science Campus
Mail Stop 1094,Ìý3065 Arlington Avenue,ÌýToledo, OH 43614-5807Ìý
Phone: 419.383.6557
Fax: 419.383.3526Ìý
Email: a.jayasuriya@utoledo.edu Ìý
Research Interests:
I am a Professor in the Department of Orthopaedic Surgery at the University of Toledo ÃÛÌÒ´«Ã½ of Medicine, with an adjunct faculty appointment in the Department of Bioengineering. My research program is interdisciplinary and focuses on developing innovative technologies to promote bone regeneration, improve bone health, and prevent skeletal complications.
My laboratory investigates injectable bone graft materials and biomaterials for the regeneration and repair of damaged bone tissue. We develop advanced approaches for the localized and controlled delivery of therapeutics, including drugs, antibiotics, growth factors, and cells. A major area of our work involves incorporating osteoinductive bone morphogenetic protein-9 (BMP-9) into microparticle-based delivery systems. By tuning the release of BMP-9 to achieve sustained delivery rather than an initial burst release, we aim to enhance bone formation and remodeling at fracture sites. We also utilize 3D printing and 3D bioprinting technologies to develop viable bone tissue constructs and organoid models for studying bone regeneration and developing new therapeutic strategies.
More recently, my research has expanded into artificial intelligence (AI) and machine learning (ML), with a focus on bone health assessment, early detection of osteoporosis, and fracture risk prediction. By integrating medical imaging with clinical data, I develop AI-driven approaches to identify early signs of compromised bone health and better characterize an individual's risk of future fractures. This work aims to advance personalized, data-driven approaches to osteoporosis prevention and fracture risk reduction, particularly in older adults.
Together, these research efforts bridge regenerative medicine, biomaterials, bioengineering, 3D bioprinting, and AI to develop innovative approaches for improving bone health, treating skeletal injuries, and ultimately preventing fractures.Ìý
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