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[(strain)-319(demonstrated)-319(the)-319(greatest)-319(sensorimotor)-319(ability)111(,)]TJ T* [(and)-257(the)-257(COP)-239(and)-257(MNS)-257(strains)-257(demonstrated)-257(the)-257(least.)]TJ T* [(When)-240(evaluated)-240(by)-240(gender)74(,)-240(the)-240(magnitude)-240(of)-240(the)-240(di)10(f)28(fer)18(-)]TJ T* [(ence)-249(in)-248(sensorimotor)-249(performance)-249(between)-248(the)-249(low)-248(and)]TJ T* [(high)-500(strains)-500(ranged)-500(from)-500(3-)-500(to)-500(13-fold)-500(on)-500(the)-500(three)]TJ -0.0074 Tc T* [(operationally)-192(de\256ned)-192(tests)-192(of)-192(sensorimotor)-192(ability)111(.)-192(These)]TJ 0 Tc 0 -1.1 TD [(wide)-279(di)10(f)28(ferences)-279(suggest)-279(that)-279(the)-279(PVG,)-279(COP)129(,)-279(and)-279(MNS)]TJ T* [(strains)-276(can)-276(be)-276(utilized)-276(as)-276(models)-276(to)-276(explore)-276(the)-276(genetic)]TJ T* [(basis)-233(of)-233(variation)-233(in)-233(sensorimotor)-233(ability)111(.)]TJ /T1_2 1 Tf -0.0001 Tc 7.982 0 0 7.982 311.987 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[(the)-334(Medical)-334(ÃÛÌÒ´«Ã½)-334(of)-334(Ohio)-334(\(T)92(oledo,)-334(OH\).)-334(The)-334(seven)-334(strains)]TJ T* [(obtained)-516(from)-516(Harlan)-516(Sprague)-516(Dawley)-516(were)-461(ACI/SegHsd,)]TJ 0.0157 Tc T* [(AUG/OlaHsd,)-680(BUF/NHsd,)-680(COP/Hsd,)-680(DA/OlaHsd,)-680(F344/)]TJ 0 Tc T* [(NHsd,)-271(and)-271(PVG/OlaHsd.)-271(The)-271(strains)-271(obtained)-271(from)-271(Dr)74(.)-271(John)]TJ T* [(Rapp)-379(were)-379(the)-379(LEW)111(,)-379(WKY)111(,)-379(SR/Jr)74(,)-379(and)-379(MNS.)-324(Animals)-379(were)]TJ T* [(housed)-327(two)-327(rats)-327(per)-327(cage;)-327(only)-327(rats)-327(of)-327(the)-327(same)-327(gender)74(,)-327(age,)]TJ T* [(and)-315(strain)-315(were)-315(housed)-315(together)74(.)-315(The)-315(rats)-315(were)-315(housed)-315(on)-315(a)]TJ T* [(12:12-h)-392(light-dark)-392(cycle)-392(with)-392(the)-392(light)-392(cycle)-392(occurring)-392(from)]TJ 0 -1.111 TD 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[(cm)-576(deep\))-576(that)-576(was)-576(set)-576(at)-576(an)-576(initial)-576(angle)-576(of)-576(22\311)-576(to)-576(the)]TJ T* [(horizontal.)-283(At)-338(the)-338(start)-338(of)-338(the)-338(test)-338(the)-338(rat)-338(was)-338(placed)-338(in)-338(the)]TJ T* [(pan)-471(on)-471(the)-471(side)-471(set)-471(at)-471(22\311,)-471(with)-471(the)-471(long)-471(axis)-471(of)-471(its)-471(body)]TJ T* [(parallel)-248(to)-248(the)-248(open)-248(edge)-248(of)-248(the)-248(pan.)-248(The)-248(angle)-248(of)-248(the)-248(pan)-248(was)]TJ T* [(then)-330(increased)-330(by)-330(2\311)-330(ever)]TJ 0.3305 Tc 11.869 0 Td [(y5st)331(oam)]TJ 0 Tc 5.542 0 Td [(aximum)-330(of)-330(47\311)-330(at)-330(75)-330(s.)]TJ -17.411 -1.111 Td [(The)-250(time)-250(from)-250(when)-250(the)-250(rat)-250(was)-250(placed)-250(in)-250(the)-250(pan)-250(until)-250(it)-250(fell)]TJ T* [(into)-526(a)-526(padded)-526(box)-526(was)-526(recorded)-526(as)-526(the)-526(third)-526(measure)-526(of)]TJ T* [(sensorimotor)-233(ability)111(.)]TJ 1.111 -1.111 Td [(For)-207(all)-207(three)-207(tests,)-207(if)-207(the)-207(rat)-207(failed)-207(to)-207(remain)-207(on)-207(the)-207(cylinder)]TJ -1.111 -1.111 Td [(or)-294(on)-294(the)-294(inclined)-294(side)-294(of)-294(the)-294(pan)-294(for)-294(at)-294(least)-294(5)-294(s,)-294(the)-294(rat)-294(was)]TJ T* [(allowed)-400(two)-400(more)-400(attempts.)-400(If)-400(after)-400(three)-400(attempts)-400(the)-400(rat)]TJ T* [(failed)-212(to)-212(remain)-212(on)-212(the)-212(cylinder)-212(or)-212(the)-212(inclined)-212(pan)-212(for)-212(at)-212(least)]TJ T* [(5)-330(s,)-330(a)-330(score)-330(of)-330(zero)-330(was)-330(recorded.)-330(In)-330(all)-330(tests,)-330(only)-330(7%)-330(of)-330(the)]TJ T* [(trials)-233(resulted)-233(in)-233(a)-233(score)-233(of)-233(zero.)]TJ /T1_0 1 Tf 0 -2.121 TD [(Data)-249(Analyses)]TJ /T1_1 1 Tf 1.111 -1.889 Td [(For)-408(each)-408(rat,)-408(the)-408(single)-408(best)-408(performance)-408(out)-408(of)-408(the)-408(\256ve)]TJ -1.111 -1.111 Td [(daily)-214(trials)-214(for)-214(each)-214(test)-214(was)-214(used)-214(as)-214(the)-214(measure)-214(most)-214(closely)]TJ 0 -1.111 TD [(associated)-345(with)-345(the)-345(genetic)-345(component)-345(of)-345(sensorimotor)-345(abil-)]TJ T* [(ity)111(.)-369(This)-369(idea)-369(of)-369(estimating)-369(the)-369(genetic)-369(component)-369(from)-369(the)]TJ 0 -1.111 TD [(best)-217(performance,)-217(rather)-217(than)-217(\(for)-217(example\))-217(the)-217(average)-217(of)-217(all)]TJ T* [(trials,)-542(has)-542(two)-542(origins.)]TJ /T1_0 1 Tf 11.686 0 Td (1)Tj /T1_1 1 Tf 0.612 0 Td [(\))-542(The)-542(environment)-542(can)-542(have)-542(an)]TJ -12.298 -1.111 Td [(in\256nite)-226(negative)-226(in\257uence)-226(on)-226(performance)-226(\(i.e.,)-226(a)-226(detrimental)]TJ T* [(environment)-276(can)-276(take)-276(the)-276(performance)-276(to)-276(0\).)-276(Factors)-276(such)-276(as)]TJ T* [(subtle)-298(di)10(f)28(ferences)-298(in)-298(housing)-298(or)-298(daily)-298(handling)-298(could)-298(cause)-298(a)]TJ T* [(genetically)-290(superior)-290(rat)-290(to)-290(perform)-290(below)-290(its)-290(maximal)-290(ability)]TJ T* [(on)-275(a)-275(given)-275(day)111(.)]TJ /T1_0 1 Tf 7.099 0 Td (2)Tj /T1_1 1 Tf 0.612 0 Td [(\))-275(However)74(,)-275(the)-275(environment)-275(can)-275(have)-275(only)-275(a)]TJ -7.711 -1.111 Td [(\256nite)-393(positive)-393(in\257uence)-393(on)-393(sensorimotor)-393(performance.)-393(That)]TJ T* [(is,)-413(environmental)-413(in\257uences)-413(cannot)-413(cause)-413(a)-413(rat)-413(to)-413(perform)]TJ 29.333 73.907 Td [(above)-327(its)-327(genetically)-327(determined)-327(upper)-327(limit)-327(of)-327(ability)111(.)-327(Thus)]TJ 0 -1.111 TD [(the)-438(rat')37(s)-438(best)-438(performance)-438(comes)-438(closest)-438(to)-438(the)-438(genetically)]TJ T* [(determined)-269(upper)-269(limit)-269(of)-269(its)-269(ability)111(.)-269(Because)-269(our)-269(goal)-269(was)-269(to)]TJ T* [(look)-559(for)-559(genetically)-559(determined)-559(di)10(f)28(ferences)-559(in)-559(phenotypes)]TJ T* [(between)-260(inbred)-260(strains,)-260(we)-260(used)-260(the)-260(best)-260(performance)-260(rather)]TJ 0 -1.111 TD [(than)-233(the)-233(average.)]TJ 1.111 -1.111 Td [(The)-380(mean)-380(value)-380(of)-380(the)-380(best)-380(performances)-380(was)-380(calculated)]TJ -1.111 -1.111 Td [(for)-232(each)-232(strain,)-232(and,)-232(for)-232(each)-232(sensorimotor)-232(test,)-232(the)-232(data)-232(were)]TJ T* [(analyzed)-252(by)-252(a)-252(two-way)-197(ANOV)111(A)-197(with)-252(strain)-252(and)-252(gender)-252(as)-252(the)]TJ T* [(independent)-301(variables.)-301(If)-301(the)-301(di)10(f)28(ference)-301(between)-301(strains)-301(was)]TJ T* [(signi\256cant,)-342(then)-342(the)-342(strain)-342(with)-342(the)-342(lowest)-342(mean)-342(value)-342(was)]TJ T* [(compared)-286(with)-286(all)-286(other)-286(strains)-286(by)-286(the)-286(post)-286(hoc)-286(Dunnett)-286(test)]TJ T* [(at)-405(a)-405(5%)-405(signi\256cance)-405(level.)-405(T)92(o)-405(test)-405(for)-405(gender)-405(e)10(f)28(fects,)-405(di)10(f)28(fer)18(-)]TJ T* [(ences)-265(between)-265(strains)-265(were)-265(compared)-265(by)-265(the)-265(Bonferroni)-265(test.)]TJ T* [(T)92(o)-549(determine)-549(if)-549(any)-549(learning)-549(e)10(f)28(fect)-549(occurred)-549(during)-549(test-)]TJ 0 -1.111 TD [(ing,)-480(a)-480(regression)-480(analysis)-480(was)-480(carried)-480(out)-480(comparing)-480(per)18(-)]TJ 0 -1.111 TD [(formance)-567(for)-567(each)-567(of)-567(the)-567(tests)-567(to)-567(trial)-567(\(day\))-567(number)-567(for)]TJ T* [(the)-537(5)-537(consecutive)-537(days)-537(of)-537(testing.)-537(Data)-537(are)-537(presented)-537(as)]TJ T* (means)Tj /T1_2 1 Tf 3.251 0 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[(performance.)-434(For)-434(the)-434(females,)-434(the)-434(PVG,)-434(BUF)111(,)-434(SR/Jr)74(,)]TJ T* [(F344,)-234(WKY)111(,)-234(and)-234(LEW)-234(strains)-234(remained)-234(on)-234(the)-234(cylinder)]TJ -0.033 Tc T* [(signi\256cantly)-178(longer)-178(than)-178(the)-178(COP)-160(strain)-178(\()]TJ /T1_1 1 Tf 0 Tc 17.454 0 Td (P)Tj /T1_2 1 Tf 0.812 0 Td (,)Tj /T1_0 1 Tf -0.033 Tc 0.978 0 Td [(0.05;)-178(Fig.)-178(2)]TJ /T1_1 1 Tf 0 Tc 4.604 0 Td (A)Tj /T1_0 1 Tf -0.0031 Tc 0.753 0 Td (\).)Tj /T1_1 1 Tf 0 Tc -23.602 -1.1 Td (Males)Tj /T1_0 1 Tf 2.739 0 Td [(.)-276(Figure)-275(2)]TJ /T1_1 1 Tf 4.459 0 Td (B)Tj /T1_0 1 Tf 0.998 0 Td [(shows)-275(the)-275(best)-275(performance)-275(on)-275(the)]TJ -9.195 -1.1 Td [(two-direction)-271(rotation)-271(test)-271(for)-271(the)-271(males)-271(of)-271(each)-271(strain.)]TJ ET q 359.9998932 0 0 409.9998932 48.5688019 318.0075073 cm /Im0 Do Q BT /T1_0 1 Tf 7.982 0 0 7.982 420.746 551.738 Tm [(Fig.)-337(1.)-556(No.)-337(of)-337(seconds)-337(each)-337(strain)-337(was)]TJ -0.0001 Tc 0 -1.125 TD [(able)-424(to)-424(remain)-424(on)-424(the)-424(cylinder)-424(in)-424(the)]TJ 0 Tc T* [(one-direction)-235(rotation)-235(test.)-235(Mean)-235(of)-235(the)]TJ T* [(best)-304(performance)-304(for)-304(each)-304(strain)]TJ /T1_2 1 Tf 15.389 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 1.137 0 Td (SE)Tj -0.004 Tc -16.526 -1.125 Td [(is)-195(shown.)]TJ /T1_1 1 Tf 0 Tc 4.378 0 Td (A)Tj /T1_0 1 Tf -0.004 Tc 0.7 0 Td [(,)-195(females;)]TJ /T1_1 1 Tf 0 Tc 4.467 0 Td (B)Tj /T1_0 1 Tf -0.004 Tc 0.718 0 Td [(,)-195(males.)-195(*)-104(Strains)]TJ 0 Tc -10.263 -1.125 Td [(in)-225(which)-225(performance)-225(was)-225(signi\256cantly)]TJ -0.0057 Tc T* [(greater)-193(than)-193(that)-193(of)-193(the)-193(lowest-perform-)]TJ 0 Tc T* [(ing)-232(strain.)]TJ 9.978 0 0 9.978 48.569 220.935 Tm [(T)62(able)-250(1.)]TJ /T1_1 1 Tf 4.116 0 Td [(Comparison)-250(of)-250(females)-250(and)-250(males)-250(in)-250(three)-250(tests)-250(of)-250(sensorimotor)-250(ability)]TJ ET 0 0 0 1 K 0.499 w 10 M 0 j 0 J []0 d 48.569 215.155 m 563.431 215.155 l 48.569 212.661 m 563.431 212.661 l 48.569 76.921 m 563.431 76.921 l 117.065 196.926 m 205.464 196.926 l 289.797 196.926 m 382.688 196.926 l 467.022 196.926 m 547.594 196.926 l 48.569 182.188 m 101.228 182.188 l 221.301 182.188 m 273.96 182.188 l 398.526 182.188 m 451.185 182.188 l 101.228 182.188 m 221.301 182.188 l 273.96 182.188 m 398.526 182.188 l 451.185 182.188 m 563.431 182.188 l S BT /T1_0 1 Tf 0.0001 Tc 6.985 0 0 6.985 64.616 187.427 Tm (Strain)Tj 9.491 2.11 Td [(One-Direction)-250(T)92(est)]TJ 15.24 -2.11 Td (Strain)Tj 9.82 2.11 Td [(T)71(wo-Direction)-250(T)92(est)]TJ 15.554 -2.11 Td (Strain)Tj 11.359 2.11 Td [(T)25(ilt)-249(T)92(est)]TJ -53.817 -2.11 Td [(Females)-5261(Males)-12911(Females)-5582(Males)-12876(Females)-4700(Males)]TJ -0.0001 Tc 7.982 0 0 7.982 64.406 171.961 Tm [(PVG)-4639(91)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(68)4797(1)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(1)55(1)-4087(PVG)-4430(156)]TJ /T1_2 1 Tf 0 Tc 13.521 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(13)-3967(128)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(9)-4523(PVG)-4520(76)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(26)4557(3)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (3)Tj -0.0001 Tc -59.977 -1.125 Td [(BUF)-4602(77)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(36)4797(1)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(6)-4588(BUF)-4393(142)]TJ /T1_2 1 Tf 0 Tc 13.521 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(8*)-4579(98)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(12)-3967(F344)-4352(73)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(15)4557(7)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (7)Tj -0.0001 Tc -59.977 -1.125 Td [(WKY)-4343(63)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(6*)-4297(35)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(3)-4588(SR/Jr)-3967(103)]TJ /T1_2 1 Tf 0 Tc 13.521 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(12)-4523(96)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(12)-3967(LEW)-4317(70)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(2*)-4057(52)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (3)Tj -0.0001 Tc -59.977 -1.125 Td [(F344)-4471(62)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(73)4797(3)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(1)55(1)-4087(F344)-4262(102)]TJ /T1_2 1 Tf 0 Tc 13.521 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(17)-4523(52)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(16)-3967(BUF)-4483(59)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(15)4557(9)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (3)Tj -0.0001 Tc -59.977 -1.125 Td [(ACI)-4955(57)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(85)4797(7)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(9)-4588(WKY)-4690(79)]TJ /T1_2 1 Tf 0 Tc 13.52 0 Td (6)Tj /T1_0 1 Tf 5.0787 Tc 0.944 0 Td [(66)5079(9)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(3)-4523(AUG)-4372(49)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(44)4557(1)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (6)Tj -0.0001 Tc -59.977 -1.125 Td [(SR/Jr)-4176(54)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf -0.0547 Tc 0.944 0 Td [(11)-4351(6)-55(1)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(3)-4588(LEW)-4783(74)]TJ /T1_2 1 Tf 0 Tc 13.52 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(12)-4523(33)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(5)-4523(SR/Jr)-4057(47)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(73)4557(7)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (5)Tj -0.0001 Tc -59.977 -1.125 Td [(LEW)-4436(43)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(82)4797(2)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(4)-4588(ACI)-5302(65)]TJ /T1_2 1 Tf 0 Tc 13.52 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(13)-4523(81)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(15)-3967(DA)-5187(43)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(54)4557(7)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (3)Tj -0.0001 Tc -59.977 -1.125 Td [(AUG)-4491(36)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(63)4797(7)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(3)-4588(MNS)-4764(52)]TJ /T1_2 1 Tf 0 Tc 13.52 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(7*)-4579(10)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(5)-4523(ACI)-4836(42)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(24)4557(8)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (6)Tj -0.0001 Tc -59.977 -1.125 Td [(DA)-5306(30)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(62)4797(8)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(5)-4588(AUG)-4838(44)]TJ /T1_2 1 Tf 0 Tc 13.52 0 Td (6)Tj /T1_0 1 Tf 5.0787 Tc 0.944 0 Td [(75)5079(7)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(10)-3967(WKY)-4224(40)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(23)4557(8)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (3)Tj -0.0001 Tc -59.977 -1.125 Td [(MNS)-4417(37)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(5*)-4853(8)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf 4.5885 Tc 0.944 0 Td [(3D)4589(A)-1064(4)4589(2)]TJ /T1_2 1 Tf 0 Tc 13.521 0 Td (6)Tj /T1_0 1 Tf 5.0787 Tc 0.944 0 Td [(83)5079(4)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(9)-4523(COP)-4520(31)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(43)4557(0)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (3)Tj -0.0001 Tc -59.977 -1.125 Td [(COP)-4639(37)]TJ /T1_2 1 Tf 0 Tc 8.03 0 Td (6)Tj /T1_0 1 Tf 4.7971 Tc 0.944 0 Td [(52)4797(5)]TJ /T1_2 1 Tf 0 Tc 6.576 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(4)-4588(COP)-4986(36)]TJ /T1_2 1 Tf 0 Tc 13.52 0 Td (6)Tj /T1_0 1 Tf 5.0787 Tc 0.944 0 Td [(42)5079(6)]TJ /T1_2 1 Tf 0 Tc 6.858 0 Td (6)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td [(3)-4523(MNS)-4298(22)]TJ /T1_2 1 Tf 0 Tc 12.989 0 Td (6)Tj /T1_0 1 Tf 4.5571 Tc 0.944 0 Td [(61)4557(8)]TJ /T1_2 1 Tf 0 Tc 6.337 0 Td (6)Tj /T1_0 1 Tf 0.944 0 Td (5)Tj -60.961 -1.933 Td [(Data)-318(are)-318(the)-318(means)-318(of)-318(the)-318(best)-318(performances)-318(in)-318(each)-318(strain)]TJ /T1_2 1 Tf 28.106 0 Td (6)Tj /T1_0 1 Tf 1.151 0 Td [(SE.)-263(Asterisks)-318(indicate)-318(a)-318(signi\256cant)-318(di)10(f)28(ference)-318(between)-318(females)-318(and)-318(males)]TJ -30.256 -1.125 Td (\(Bonferroni,)Tj /T1_1 1 Tf 5.823 0 Td (P)Tj /T1_2 1 Tf 0.778 0 Td (,)Tj /T1_0 1 Tf -0.0001 Tc 0.944 0 Td (0.05\).)Tj 0 Tc 9.978 0 0 9.978 534.05 744.772 Tm (R1385)Tj -0.0001 Tc 7.982 0 0 7.982 184.822 744.772 Tm [(SENSORIMOTOR)-366(DIFFERENCES)-311(AMONG)-366(INBRED)-366(STRAINS)]TJ ET 0 G 1 w /GS1 gs 588 18 16 756 re 0 0 m 0 0 m 0 0 m 0 0 m 0 0 m 0 0 m 0 0 m 0 0 m 0 0 m S 0 g /GS1 gs BT /T1_3 1 Tf 0 Tc 0 -9 9 0 593 348.9886 Tm ( on May 20, 2008 )Tj 0 0 1 rg ET /GS1 gs BT /T1_3 1 Tf 0 -9 9 0 593 439.5285 Tm (ajpregu.physiology.org)Tj 0 g ET /GS1 gs BT /T1_3 1 Tf 0 -9 9 0 593 512.5543 Tm (Downloaded from )Tj ET endstream endobj 97 0 obj<> endobj 98 0 obj<> endobj 99 0 obj[97 0 R] endobj 100 0 obj<> endobj 104 0 obj<>stream 0 0 0 1 k 1 i /GS0 gs BT /T1_0 1 Tf 0 Tc 0 Tw 0 Ts 100 Tz 0 Tr 9.978 0 0 9.978 48.569 291.234 Tm [(The)-347(PVG)-346(males)-347(exhibited)-347(the)-347(highest)-347(performance)-347(by)]TJ 0 -1.1 TD [(remaining)-365(on)-365(the)-365(cylinder)-365(for)-365(128)]TJ /T1_1 1 Tf 16.262 0 Td (6)Tj /T1_0 1 Tf 1.198 0 Td [(9)-365(s,)-365(whereas)-365(the)]TJ -17.46 -1.1 Td [(MNS)-310(males)-310(were)-310(the)-310(lowest)-310(performers,)-310(remaining)-310(on)]TJ T* [(the)-306(cylinder)-306(for)-306(only)-306(10)]TJ /T1_1 1 Tf 11.12 0 Td (6)Tj /T1_0 1 Tf 1.139 0 Td [(5)-306(s,)-306(a)-306(13-fold)-306(di)10(f)28(ference.)-306(For)]TJ -12.259 -1.1 Td [(the)-285(males,)-285(the)-285(PVG,)-285(BUF)111(,)-285(SR/Jr)74(,)-231(ACI,)-285(WKY)111(,)-231(AUG,)-285(and)]TJ 0 -1.1 TD [(F344)-531(strains)-531(remained)-531(on)-531(the)-531(cylinder)-531(signi\256cantly)]TJ T* [(longer)-233(than)-233(the)-233(MNS)-233(strain)-233(\()]TJ /T1_2 1 Tf 13.238 0 Td (P)Tj /T1_1 1 Tf 0.9 0 Td (,)Tj /T1_0 1 Tf 1.066 0 Td [(0.05;)-233(Fig.)-233(2)]TJ /T1_2 1 Tf 5.043 0 Td (B)Tj /T1_0 1 Tf 0.778 0 Td (\).)Tj -20.024 -1.1 Td [(For)-518(the)-518(two-direction)-518(rotation)-518(test,)-518(in)-518(addition)-518(to)]TJ -1 -1.1 Td [(signi\256cant)-405(strain)-405(di)10(f)28(ferences,)-405(di)10(f)28(ferences)-405(between)-405(the)]TJ T* [(genders)-620(were)-620(signi\256cant)-620(\()]TJ /T1_2 1 Tf 12.896 0 Td (P)Tj /T1_1 1 Tf 1.287 0 Td (,)Tj /T1_0 1 Tf 1.453 0 Td [(0.0001\))-620(as)-620(was)-620(the)]TJ -15.636 -1.1 Td [(gender)18(-strain)-210(interaction)-210(\()]TJ /T1_2 1 Tf 12.085 0 Td (P)Tj /T1_1 1 Tf 0.877 0 Td (5)Tj /T1_0 1 Tf 1.043 0 Td [(0.008\).)-210(T)62(able)-210(1)-210(compares)]TJ -14.005 -1.1 Td [(the)-634(mean)-634(values)-634(for)-634(the)-634(best)-634(performance)-634(on)-634(the)]TJ T* [(two-direction)-257(rotation)-257(test)-257(for)-257(males)-257(versus)-257(females.)-257(In)]TJ T* [(2)-631(of)-631(the)-631(1)55(1)-631(strains)-631(\(BUF)-631(and)-631(MNS\),)-631(the)-631(females)]TJ T* [(remained)-370(on)-370(the)-370(cylinder)-370(longer)-370(than)-370(the)-370(males)-370(\()]TJ /T1_2 1 Tf 23.333 0 Td (P)Tj /T1_1 1 Tf 1.037 0 Td (,)Tj /T1_0 1 Tf -24.37 -1.1 Td (0.005\).)Tj /T1_2 1 Tf 0 -1.8 TD [(T)71(ilt)-250(T)89(est)]TJ 1 -1.8 Td (Females)Tj /T1_0 1 Tf 3.795 0 Td [(.)-274(Again,)-328(di)10(f)28(ferences)-328(in)-328(performance)-328(between)]TJ -4.795 -1.1 Td [(strains)-403(on)-403(the)-403(tilt)-403(test)-403(were)-403(signi\256cant)-403(\()]TJ /T1_2 1 Tf 19.229 0 Td (P)Tj /T1_1 1 Tf 1.07 0 Td (,)Tj /T1_0 1 Tf 1.236 0 Td (0.0001\).)Tj -21.535 -1.1 Td [(Figure)-343(3)]TJ /T1_2 1 Tf 3.973 0 Td (A)Tj /T1_0 1 Tf 1.047 0 Td [(shows)-343(the)-343(best)-343(performance)-343(on)-343(the)-343(tilt)-343(test)]TJ -5.021 -1.1 Td [(for)-511(the)-511(females.)-511(The)-511(PVG)-511(females)-511(remained)-511(on)-511(the)]TJ 26.4 23.4 Td [(platform)-376(for)-376(the)-376(longest)-376(time)-376(\(76)]TJ /T1_1 1 Tf 15.884 0 Td (6)Tj /T1_0 1 Tf 1.209 0 Td [(2)-376(s\),)-376(whereas)-376(the)]TJ -17.093 -1.12 Td [(MNS)-233(females)-233(remained)-233(for)-233(the)-233(shortest)-233(time)-233(\(22)]TJ /T1_1 1 Tf 22.275 0 Td (6)Tj /T1_0 1 Tf 1.066 0 Td [(6)-233(s\),)]TJ -23.342 -1.12 Td [(a)-307(3.5-fold)-307(di)10(f)28(ference.)-307(The)-307(strains)-307(that)-307(remained)-307(on)-307(the)]TJ 0 -1.12 TD [(platform)-402(signi\256cantly)-402(longer)-402(than)-402(the)-402(MNS)-402(were)-402(the)]TJ T* [(PVG,)-201(F344,)-201(LEW)111(,)-201(BUF)111(,)-201(SR/Jr)74(,)-146(AUG,)-201(DA,)-146(ACI,)-201(and)-201(WKY)]TJ 0 -1.12 TD (\()Tj /T1_2 1 Tf 0.333 0 Td (P)Tj /T1_1 1 Tf 0.9 0 Td (,)Tj /T1_0 1 Tf 1.066 0 Td [(0.05;)-233(Fig.)-233(3)]TJ /T1_2 1 Tf 5.043 0 Td (A)Tj /T1_0 1 Tf 0.76 0 Td (\).)Tj /T1_2 1 Tf -7.101 -1.12 Td (Males)Tj /T1_0 1 Tf 2.739 0 Td [(.)-255(Figure)-255(3)]TJ /T1_2 1 Tf 4.417 0 Td (B)Tj /T1_0 1 Tf 0.977 0 Td 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[(vidual)-317(traits)-317(contribute)-317(to)-317(a)-317(rat')37(s)-317(ability)-317(to)-317(perform)-317(on)]TJ -0.0077 Tc T* [(these)-192(tests,)-192(such)-192(as)-192(di)10(f)20(ferences)-192(in)-192(coordination,)-192(strength,)]TJ 0 Tc T* [(fear)74(,)-307(anxiety)111(,)-307(tractability)111(,)-307(intelligence,)-307(motivation,)-307(and)]TJ T* [(subtle)-268(anatomic)-268(variations.)-268(In)-268(conscious)-268(animals)-268(these)]TJ 0 -1.1 TD [(traits)-206(are)-206(inextricably)-206(intertwined)-206(and)-206(cannot)-206(be)-206(evalu-)]TJ T* [(ated)-584(as)-584(purely)-584(independent)-584(events.)-584(There)-584(were)-584(no)]TJ ET q 359.9998932 0 0 404.9998932 48.5688019 323.0106964 cm /Im0 Do Q BT /T1_1 1 Tf 7.982 0 0 7.982 420.746 545.241 Tm [(Fig.)-337(3.)-556(No.)-337(of)-337(seconds)-337(each)-337(strain)-337(was)]TJ -0.0001 Tc 0 -1.125 TD [(able)-337(to)-337(remain)-337(on)-337(the)-337(platform)-337(for)-337(the)]TJ 0 Tc T* [(tilt)-269(test.)]TJ /T1_0 1 Tf 3.966 0 Td 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